Infectie gewrichtsprothese (PJI)/osteosynthese materiaal - streptokokken (Streptococcus spp.).
Advices
Priority | Medication | Remarks |
---|---|---|
Priority: 1st choice |
Medication: benzylpenicilline iv 6million. IU continuous per 24 hours followed by
amoxicilline po 750mg 3dd |
Remarks:
Benzylpenicilline oplaaddosering 1milj. IU iv gevolgd door continu infuus 6milj. IU/24u i.v. OF benzylpenicilline 6dd 1milj. IU i.v. |
Priority: 1st choice alternative |
Medication: benzylpenicilline iv 6million. IU continuous per 24 hours followed by
clindamycine po 600mg 3dd |
Remarks:
Benzylpenicilline oplaaddosering 1milj. IU iv gevolgd door continu infuus 6milj. IU/24u i.v. OF benzylpenicilline 6dd 1milj. IU i.v. |
Priority | Medication | Remarks |
---|---|---|
Priority: 1st choice |
Medication: cefazoline iv 3g continuous per 24 hours followed by
clindamycine po 600mg 3dd |
Remarks:
Cefazoline oplaaddosering 1g iv gevolgd door continu infuus 3g/24u iv OF cefazoline 3dd 1g iv |
Priority: 1st choice |
Medication: ceftriaxon iv 2g 1dd followed by
clindamycine po 600mg 3dd |
Remarks:
Bij viridans streptokokken (vergroenende) en pneumokokken (gezien afwezigheid van breekpunten voor cefazoline voor deze micro-organismen) |
Sources
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
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Metadata
Swab vid: G-502416.2
Updated: 03/26/2025 - 11:49
Status: Published
General comments
Algemene principes behandeling: